We design and develop approaches to modulate how the body responds to ubiquitous environmental cues to modify the course of serious diseases. Interactions with environmental stimuli, such as light, gravity, the earth’s magnetic field, food, microbes, and our atmosphere are for all practical purposes inescapable. By providing the context for genetic variation, such cues have dictated evolution. The body’s composition of small molecules, gene expression patterns and biochemical, physiological, and morphological changes can be viewed as a culmination of its adaptation to long-term universal environmental influences. Common diseases such as cancer, metabolic, cardiovascular, neurological and degenerative disorders, and aging might be associated with environmental pressures, both preventable and inescapable, rather than the result of a single genetic event.
Thus, we aim to quantify the body’s precise response to select environmental stimuli, use this information to define who we are as a species and as individuals, and then modulate these interactions to redefine the individual and change the course of disease. We focus on unavoidable environment-organism interactions that have innately shaped organisms through evolution.